In this study, we examined alterations to cellular metabolism in a previously characterized motor neuronal ALS model system, the murine neuroblastoma × spinal cord (NSC-34) cell line, stably expressing human wild-type (wt) SOD1 (wtSOD1) or mutant G93A (G93ASOD1) [13]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.