ZNF804A and schizophrenia: In particular, the rs1344706 single nucleotide polymorphism (SNP) in intron two of ZNF804A was the first variant to reach an unequivocal genome-wide significance for schizophrenia (O’Donovan et al. 2008) with later meta-analyses confirming the association and extending it to a broader psychosis phenotype (Zhu et al. 2014; Sun et al. 2015; Williams et al. 2011a, b).