It is important to note here that TCF7L2 (Transcription Factor 7-Like 2, HMG-box) has been initially abbreviated as TCF4 (T cell factor 4), and it should not be confused with a basic helix-loop-helix transcription factor TCF4 (Transcription Factor 4, alias E2-2, ITF2), which is also associated with schizophrenia. The gene discussed is TCF7L2; the disease is schizophrenia.