FABP5 and experimental autoimmune encephalomyelitis: Since fatty acids function both as energy sources and as signaling molecules, FABPs have been identified as central regulators of metabolic and inflammatory pathways [6-9] Using a mouse model of MS, experimental autoimmune encephalomyelitis (EAE), we have demonstrated that mice deficient of FABPs, in particular epidermal FABP (E-FABP), have protection from the development of EAE [10,11].