As recent studies suggest an involvement of the novel n-3 derived lipid mediator resolvin E1 (RvE1) and its receptor ChemR23 in the mediation of n-3-induced (patho-)physiological effects, we additionally subjected wild-type and ChemR23 knockout mice to a model of experimental ARDS after infusion of lipid emulsions. Here, CMKLR1 is linked to acute respiratory distress syndrome.