Variables included in the derivation of the clinical predictor score were: use of ART for at least 30 days prior to enrollment, use of PCP prophylaxis for at least 30 days prior to enrollment, temperature below 35.5°C or above 38°C, heart rate above 120 beats/minute, respiratory rate above 30 breaths/minute, oxygen saturation below 90%, and CD4 cell count below 50 cells/mm3. The gene discussed is CD4; the disease is pneumocystosis.