FOXM1 and cancer: Indeed, the thiazole antibiotics thiostrepton, which inhibits the transcriptional activity of FOXM1, has been shown to specifically target cancer cells and have lesser effects on non-cancerous cells.36 A reversible specific small molecule inhibitor of KIF20A called paprotrain [(Z)-2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile] has also been developed.