Recently, the expression of CXCR5, another chemokine receptor involved in homing of DCs to lymph nodes, and its ligand CXCL13, was linked to EMT and lymph node metastasis in breast cancer.39 Similar to this, others have found that migratory tumor cells may co-opt functional and migratory properties of macrophages in mammary tumors.40, 41. This evidence concerns the gene CXCR5 and breast carcinoma.