In addition, elevated plasmatic lipase activity in the caerulein-group (Bace1-/- mice (3.9 ± 1.9 μkat/L) and WT mice (3.8 ± 1.9 μkat/L)) was detected after 8 hours, indicating a successful induction of pancreatitis. The gene discussed is BACE1; the disease is pancreatitis.