Furthermore we aimed to evaluate frequencies of promoter (hg38/chr3: 50,267,308–50,267,797) and intronic (hg38/chr3: 50,268,972–50,269,271) CpG-island hypermethylation correlations with SEMA3B expression, and tumor progression in lung and renal cancers. This evidence concerns the gene SEMA3B and renal carcinoma.