EGFR and neoplasm: Significant enrichment was also found for growth promoting and tumor progression pathways such as EGFR, MYC, VEGFR and E2F; for biological processes linked to proliferation such as telomere maintenance, cell cycle, DNA repair, DNA replication chromosome organization; and for gene sets associated with ductal invasive breast cancer and exposure to EGF or MYC activity (Fig 2A).