Meier et al. found that leptin could induce the expression and secretion of IP-10 in a human monocytic cell line and in peripheral blood mononuclear cells34, and Jain et al. reported that plasma IP-10 levels were positively associated with plasma levels of leptin in type 2 diabetic patients21. The gene discussed is CXCL10; the disease is type 2 diabetes mellitus.