ARHGAP5 and metastatic malignant neoplasm in the lymph nodes: We found that the average expression level of ARHGAP5 was upregulated in late-stage NPC (P = 0.0192, Figure 6b) in comparison with the early-stage NPC, and NPC with advanced lymph node metastasis (N2/N3 stage) had higher expression of ARHGAP5 (P = 0.0216, Figure 6c).