In the meanwhile, CaMKIIγ could directly or indirectly upregulate multiple signaling pathways such as extracellular signal-regulated kinase 1/2 (Erk1/2), protein kinase B (Akt1), Stat3, and β-catenin and involve in regulating the survival and proliferation of NSCLC cells [5]. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.