However, ARG-1 concentration was significantly higher in stage 4 (22.49 ± 5.41 pg/mL) than in non-stage 4 (8.2 ± 5.1 pg/mL, P = 0.01) NB patients (Figure 4(b)), suggesting that ARG-1 release may be related to a more advanced disease stage. Here, ARG1 is linked to neuroblastoma.