However, garlic powder exerts no detectable effects on CRP, TNF-α, ICAM-1, lipid concentrations, and risk markers for inflammatory processes associated with subjects with atherosclerosis and CVD [99]; additionally, AGE does not change plasma cholesterol level or ICAM-1 expression in a rabbit model of atherosclerosis [100]. The gene discussed is ICAM1; the disease is atherosclerosis.