The other demographic (age, sex), clinical (disease duration, therapy for DM, BMI, WC, hypertension, hypercholesterolemia, and hypertriglyceridemia), and metabolic variables (serum fasting glucose, HbA1c, creatinine, and UAE) did not significantly differ according to the presence or absence of raised IL-6 and IL-10 (Table 1). This evidence concerns the gene IL10 and diabetes mellitus.