FOXA1 exhibited the most widespread methylation in basal-like tumours, with hypermethylation encompassing two separate regions; a very large region covering much of the FOXA1 gene body and ending approximately 6 kb downstream of the transcription termination site (region A) and a shorter region approximately 2 kb upstream of the transcription start site (region B). The gene discussed is FOXA1; the disease is neoplasm.