The percentage of circulating CD4+CD161+ (22.19, 18.41–29.44%) (median, interquartile range) and CD8+CD161+ cells (19.90, 16.26–29.74%) in RA patients was not different from HC (20.34, 18.35–22.58%, and 19.27, 17.19–24.27%; P = 0.122 and P = 0.675, resp). The gene discussed is CD8A; the disease is rheumatoid arthritis.