However, Yildirim et al. rolled out patients exposed to mediastinal irradiation from the study [49], but we included them as a separate group, so, to the best of our knowledge, our study is the first to investigate the role of NT-proBNP and TDI (both pulsed and color coded) for detection of late cardiotoxicity induced by anthracyclines and mediastinal irradiation in childhood cancer survivors. Here, NPPB is linked to childhood malignant neoplasm.