The longer survival of patients carrying HNSCC with higher AChE and lower BChE (Fig. 1e-f) agreed with the findings of others for post-stroke patients [51], whose survival pace was related with higher serum AChE activity and lower BChE activity, and differed from the prospects of patients who underwent cardiovascular events, whose survival was found associated with higher serum AChE and BChE activities [52]. This evidence concerns the gene ACHE and stroke disorder.