IGHE and allergic disease: Levels of allergen-specific IgE antibodies in children with HDM allergy were highest for rDer p 2 (medians: all, 15.1 ISU; asthmatic children, 19.9 ISU; nonasthmatic children, 11.4 ISU), followed by rDer p 5 (medians: all, 13.1 ISU; asthmatic children, 16.5 ISU; nonasthmatic children, 4.7 ISU) and nDer p 1 (medians: all, 13.1 ISU; asthmatic children, 15.3 ISU; nonasthmatic children, 8.6 ISU; Fig 2).