In agreement with the fact that fewer asthmatic patients had allergen-specific IgG responses and higher levels of allergen-specific IgE in the asthma group, the correlation between allergen-specific IgE and IgG levels was weaker for the asthmatic group than for the group of nonasthmatic subjects for most of the tested allergens (nDer p 1: ρ = 0.69, P < .0001; rDer p 2: ρ = 0.64, P < .001; rDer p 7: ρ = 0.37, P < .001; rDer p 10: ρ = 0.07, P = .502; and rDer p 23: ρ = 0.53, P < .001). The gene discussed is IGHE; the disease is asthma.