ABCC8 and type 2 diabetes mellitus: It has been hypothesized that the rs5219 (p.E23K) variation in the 11p15.1 region may play an important role in the development of T2DM, thus making it a popular marker to assess inKCNJ11.However, to date the influence of ABCC8 SNPs on the susceptibility to T2DM has not been well-characterized.