The ONCOMINE Cancer Profiling Database showed that Bbf2h7 expression is significantly upregulated in glioblastoma, invasive ductal breast carcinoma, cervical squamous carcinoma, prostate adenocarcinoma and colon adenocarcinoma, but it is unchanged in gastric and pancreatic adenocarcinomas even though their cell proliferation is known to be promoted by activation of Hh signaling [23,24]. This evidence concerns the gene CREB3L2 and glioblastoma.