IRAK1 and infection: Consequently, since significant targeting of TLR2 by miR-UL112-3p does not occur earlier than 2–3 days post-infection—long after the cells have become unresponsive to TLR2 signaling—we could not test how lack of miR-UL112-3p affects TLR2 signaling (including IRAK1 and NFκB activation) in the context of HCMV infection.