GRIN2A and systemic lupus erythematosus: Anti-NR2A/B antibodies from 14 SLE patients, affinity-purified using a DWEYSVWLSN peptide-conjugated sepharose column, up-regulated the expression of endothelial leukocyte adhesion molecule 1, vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 on endothelial cells via the activation of NF-κB signaling pathway [40].