CD8A and central nervous system cancer: Fig 6A shows the dynamics of CD8+ T cells and it is observed from the figure that the cell count increases gradually till 180 days (till the 6th month) and then, there is a sharp decline, which points to the fact that though T-lymphocytes tries to counterattack the glioma cells, its cytotoxic efficacy sharply decreases in the 8th month with maximum decrease observed in the 10th month (see Fig 6B).