We have estimated the values of the growth rate (r2) of macrophages, the activation rate (a1) of macrophages due to interaction with the IFN-γ and elimination term (α3) of the macrophages due to interaction with glioma cells are 0.3307 h−1, 0.1163 h−1 cells.pg and 0.0194 h−1 respectively. The gene discussed is IFNG; the disease is glioma.