Kronik et al. [25] considered the interactive dynamics of cytotoxic T-Lymphocytes, brain tumor cells, major histocompability complex (MHC) class-I and MHC class-II along with cytokines TGF-β and IFN-γ, where they have used computer simulation for model verification and retrieving putative treatment scenarios. This evidence concerns the gene TGFB1 and brain neoplasm.