CD8A and malignant glioma: To examine potential approaches towards achieving glioma eradication with T11 target structure as a potent immune stimulator, we develop a mathematical model involving immune components, namely, macrophages, CD8+ T cells, TGF − β and IFN − γ. The sensitivity analysis has been performed on the system parameters, which indicates r1 (growth rate of malignant glioma cells) to be the most sensitive parameter.