ACKR3 and neuroblastoma: Moreover, while neither CXCR4 nor CXCR7 displayed any significant effect on NB cell homing to the BM, a strongly enhanced eGFP signal was observed in the BM of NB8x4x7 group of mice (Fig 2), suggesting a positive effect of the coexpression of CXCR4 and CXCR7 receptors on NB cell dissemination to the BM.