To explore the function of CD82 in CD34+/CD38− AML cells, CD34+/CD38- cells isolated from AML patients (n = 3, cases #1–3) were transduced with CD82-specific shRNA and their gene expression profiles were compared to the cells transduced with control shRNA by microarray analysis (GSE64527). The gene discussed is CD82; the disease is acute myeloid leukemia.