TNF and inflammatory bowel disease: Since the therapeutic potential of Boswellia in IBD is still under debate, in this study Boswellia serrata oleo-gum resin extract (BSE) and its derivative AKBA were evaluated in Caco-2 cell monolayer exposed to H2O2 or to INF-γ+TNF-α, chosen as experimental model of endogenous inflammatory stimuli [21].