Diagnosis may involve the Bent III and Kuhn criteria [8]: (1) nasal polyps, (2) sinus content positive for fungi on staining and/or cultures, (3) eosinophil rich mucin, (4) no evidence of invasive disease but positive CT findings of sinus expansion or opacification, and (5) evidence of allergic sensitivity in either skin testing or serum IgE specific to fungi (with skin testing showing greater sensitivity than serum IgE testing [1]). The gene discussed is MUC5AC; the disease is Nasal polyposis.