GAS5 and cancer: GAS5 is down-regulated in a number of cancers, such as breast cancer (Mourtada-Maarabouni et al., 2009), renal cell carcinoma (Qiao et al., 2013), pancreatic cancer (Lu et al., 2013), bladder cancer (Liu et al., 2013b), non-small-cell lung cancer (Shi et al., 2013), gastric cancer (Sun et al., 2014), malignant pleural mesothelioma (Renganathan et al., 2014), hepatocellular carcinoma (Tu et al., 2014).