BMP7 and kidney disorder: The fact that renal BMP-7 disappears during renal fibrogenesis (Wang et al., 2001; Morrissey et al., 2002; Yang et al., 2007) and, supply of BMP-7 either exogenously or endogenously results in prevention or even reversal of functional and structural changes of various nephropathies in animal models (Vukicevic et al., 1998; Hruska et al., 2000; Wang et al., 2003, 2006; Zeisberg et al., 2003a,b; Chan et al., 2008), strongly promises a renal protective function of BMP-7 in human kidney disorders.