Therefore, dietary supplements, such as QCT and CUR, which reduce NADPH oxidase activity in several preclinical models of atherosclerosis are considered potential adjuvant agents in the prevention or chronic treatment of cardiovascular diseases (Deby-Dupont et al., 2005; Sánchez et al., 2006; Romero et al., 2009). Here, FMO5 is linked to atherosclerosis.