GC extract as drug of known brand name and manufacturer (2–3 capsules/day for 42 days). To increase bile flow after cholecystectomy 20 years ago as indication for treatment. Latency period of 42 days with itching and jaundice as symptoms. ALT 461 U/L, AST 355 U/L, ALP 260 U/L, normalization not reported. After GC discontinuation, on day 12 ALT 235 U/L. Exclusion of hepatitis A–C and of infections by CMV, EBV, HSV, and VZV. AMA negative, exclusion of autoimmune hepatitis reported but individual parameters not described. Upon sonography and ERCP normal bile ducts after cholecystectomy. This evidence concerns the gene GPT and autoimmune hepatitis.