• 42-year old Japanese woman (Itoh et al., 1995): Xia Chai Hu Tang 7.5 g daily for an unspecified time period to treat hepatitis A infection. Symptoms not specified, ALT 2 165 U/L (normal < 35) initially dropped with treatment to 42 U/L and increased 3 weeks after initiation of treatment. ALT 1335 U/L with normalization within 2 months after withdrawal. Intentional 2-day reexposure: ALT 195 U/L ALTb < 5N and ALTr = 2ALTb → positive reexposure. The gene discussed is GPT; the disease is hepatitis A virus infection.