APOE and Alzheimer disease: We calculated the general across-domain IIV and found that it did not vary with APOE status in HCS [F(1,75) = 0.412; p = 0.37; η2 = 0.003], MCI [F(1,51) = 0.316; p = 0.54; η2 = 0.008], or AD [F(1,33) = 0.012; p = 0.87; η2 = 0.00].