IDH1 and glioma: Homozygous deletions in these genes co-occur with IDH1 mutations in glioblastoma patients (Figure 5, Fisher test P-value < 0.0001 for the 14 different CNAs, co-occurrence odds ratio > 10), and to a lesser extent in lower grade glioma (co-occurrence odds ratios 2–10 for 10 CNAs, but not significant), but not in uterine, breast, ovarian, head and neck, lung, colon or kidney cancer patients (Supplementary Figure S9).