Select examples of undesirable tumor cells gene responses, shown in Table 1B, include the induction of CEACAM1, an interferon-inducible immune-inhibitory adhesion molecule [94], EREG, which induces glioma cell growth [95], and IDO1, an interferon-inducible immunosuppressive factor that is particularly active in glioma [96]. Here, IDO1 is linked to central nervous system cancer.