The weight and the volume of tumor were almost identical between the two groups (Fig. 5a), and expression of CNTN-1 was further demonstrated to be downregulated, while E-cadherin expression upregulated in the sh#2 group in xenograft tumors (Fig. 5b), suggesting that CNTN-1 was not essential for tumor formation by these cells. This evidence concerns the gene CNTN1 and neoplasm.