The level of serum γ-glutamyltransferase (GGT), a widely used index for excessive alcohol consumption and/or liver dysfunction, has been found to be associated with an increased risk of diabetes, metabolic syndrome and cardiovascular disease (CVD), including hypertension, coronary heart disease (CHD) and heart failure (HF), as well as both cardiovascular and all-cause mortality [1-5]. The gene discussed is GGT1; the disease is coronary artery disorder.