Since the association of GRS-7, which included the information of these 6 SNPs in addition to that of rs12571751 in ZMIZ1 locus, with the disease was stronger than that of rs12571751 alone, it is suggested that these 6 loci have some effects on conferring susceptibility to type 2 diabetes also in the Japanese population. The gene discussed is ZMIZ1; the disease is type 2 diabetes mellitus.