Subsequently, in a sex-differentiated analysis followed by a meta-analysis, rs11063069 near the cyclin D2 gene (CCND2) and rs8108269 near the gastric inhibitory polypeptide receptor gene (GIPR) were shown to be associated with type 2 diabetes with a genome-wide significance level, and the effect of CCND2 locus was stronger in male, whereas the association of the GIPR locus was more significant in female [16]. The gene discussed is GIPR; the disease is type 2 diabetes mellitus.