In order to further assess the role of ENO1 in EC, we measured the expression levels and subcellular localization of ENO1 protein in 20 normal NE tissues, 22 endometrial atypical hyperplasia (EAH) and 100 archived paraffin-embedded EC samples using immunohistochemical staining (Figure 8A). Here, ENO1 is linked to atypical endometrial hyperplasia.