PROM1 and neuroblastoma: Having noted that JARID1B expression was linked to the stem cell-like attributes and metastatic potential of NB cells, we further validated our findings by flow-cytometric correlative analysis of JARID1B and known stem cell markers, ALDH, CD133 and SP cell sorting, all of which demonstrated that JARID1B knockdown negatively modulated stemness markers including ALDH, SP and CD133 expression (Fig 7A, 7B and 7C).