Since ALDH1B1 is overexpressed in human colon cancer and appears to be associated with activation of Wnt/β-catenin pathway, we analyzed the human ALDH1B1 3kb promoter region using the Transcription Element Search System (TESS) program (www.cbil.upenn.edu/cgi-bin/tess/). Here, ALDH1B1 is linked to malignant colon neoplasm.