A 582 kb microdeletion encompassing exon 1 of the gene encoding the RAR-related orphan receptor B (RORB; 9q21.13, chr9: 77,112,251–77,303,533, NM_006914, hg19) was found in a male patient with childhood absence epilepsy, overlapping with the critical region of a novel microdeletion syndrome at 9q21.13 characterised by intellectual disability, speech delay, facial dysmorphisms and epilepsy [63]. The gene discussed is RORB; the disease is Intellectual disability.