Three of the epilepsy-associated microdeletions have been reported in two previous publications demonstrating an association of microdeletions affecting the 5 ́-terminal exons of the neuronal genes encoding the adhesion molecule neurexin 1 (NRXN1; 2p16.3, chr2: 50,145,642–51,259,673, hg19) and the splicing regulator RNA-binding protein fox-1 homolog (RBFOX1; 16p13.3, chr16: 5,289,468–7,763,341, hg19) [26,27]. Here, RBFOX1 is linked to epilepsy.