HLA-C and autoimmune hepatitis: Its definitive pathogenesis is uncertain, but it is widely believed that an environmental agent triggers an autoimmune process in genetically predisposed individuals.5 Environmental triggers include viruses, immunizations, herbs, and an array of medications and drugs.30 The primary genetic associations with autoimmune hepatitis pertain to the HLA region of the major histocompatibility complex (MHC) locus on chromosome six.31 The clinical manifestations of disease are variable and an individual's symptomatology can follow an undulating course.