Researchers also found an altered DNA methylation pattern in the myocardia of patients with idiopathic DCM, causing the misexpression of the genes for lymphocyte antigen 75 (LY75) and the tyrosine kinase-type cell surface receptor HER3 (ERBB3), the zebrafish orthologues of which are important for both adaptive and maladaptive responses in HF [56]. This evidence concerns the gene ERBB3 and familial dilated cardiomyopathy.