MAPK3 and non-small cell lung carcinoma: Then, we detected the phosphorylation of three parallel signal transduction modules, including JNK, p38, and ERK, in MAPK signaling and found the phosphorylation of ERK1/2 was significantly enhanced in ILT4 overexpressing NSCLC cells (Figure 4B) and inhibited in ILT4 knockdown cells (Figure 4C).