Previously we showed AAE exerted its anti-cancer effect in several prostate cancer cell lines in vitro and LNCaP tumors in vivo, and identified a compound with anti-proliferative and anti-androgen receptor functions: Ericifolin, [Eugenol 5-O-β-(6′-galloylglucopyranoside)], from AAE [18]. The gene discussed is AR; the disease is Familial prostate cancer.