The research group has detected lower vaspin levels in subjects with carotid stenosis, having undergone an ischemic vascular event in the last 3 months as compared to those with asymptomatic stenosis, and the lowest levels have been found in subjects with the most recent vascular event, whereas circulating vaspin levels have not correlated with the severity of atherosclerosis [52]. This evidence concerns the gene SERPINA12 and atherosclerosis.