Ye et al. have reported higher vaspin levels in subjects with T2DM and a positive correlation between vaspin and postprandial blood glucose levels [57, 58], as Li et al. described a lowering effect of continuous subcutaneous insulin infusion on serum vaspin concentrations concomitantly with the beta-cell function amelioration in T2DM [58]. Here, SERPINA12 is linked to type 2 diabetes mellitus.