APP and Alzheimer disease: On the basis of EEG morphology, no differences in SWDs were observed between mouse strains, and the frequency of SWDs was not found to be significantly different between the two mouse models (APP/PS1 mean: 5 ± 1 SWDs/hr versus 3xTg-AD mean: 11 ± 6 SWDs/hr; P = 0.2 by Student’s t-test).